Big Fat Negative: TTC, Infertility and IVF

Big Fat Negative: TTC, Infertility and IVF

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Big Fat Negative: TTC, Infertility and IVF
Big Fat Negative: TTC, Infertility and IVF
Maybe IUI isn’t as useless as we thought

Maybe IUI isn’t as useless as we thought

It’s cheaper and less invasive than IVF – and for a very specific group of people, IUI might just provide the answer they needed.

Emma Haslett's avatar
Emma Haslett
May 09, 2025
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Big Fat Negative: TTC, Infertility and IVF
Big Fat Negative: TTC, Infertility and IVF
Maybe IUI isn’t as useless as we thought
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Good morning!

Today I am addressing a subject I have actively dismissed on the podcast on multiple occasions: IUI. But actually, for a small group of fertility patients, there’s a chance it might be the solution to their problems.

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Have a lovely weekend! We’ll see you on Tuesday.

Emma xxx

red fruit with white background
This is not the last time you will see this stock photo. Photo by Deon Black on Unsplash

Look, I hold my hands up: I have, historically, been pretty rude about intrauterine insemination (IUI), the process of injecting sperm directly into the uterus.

For certain people – same-sex couples with no history of infertility using donor sperm, for example, or people who struggle to make love (forgive this euphemism – there are certain spam-tastic words one simply cannot use in an email), or single women (also using donor sperm) – it’s a great idea. For anyone else, it has always seemed to me to be a little… well, pointless.

But then I thought about it. The average cost of a cycle of IUI is a fraction of that of IVF – at my clinic it’s £1,400 for an IUI cycle, compared with upwards of £4,500 for IVF. We’re living in an expensive world right now. Maybe, before I dismissed it altogether, I should have looked into IUI more. Because for a very certain group of people, it just might solve their problems and keep their savings intact.

Success factors

There isn’t a lot of data out there about how many fertility treatment cycles are IUI, but it is definitely less popular than it was, says Holly Exeter, a senior embryologist at CRGH Portland.

“For most patients, the journey to getting fertility treatment is a long one,” she says. “By the time they are choosing to come for treatment, a success rate of less than 11% does not sound worth the time it would take to finally start a family.”

Well, quite. That’s one of the reasons I was so rude about IUI: I didn’t understand the difference between it and love-making (sorry, sorry). Surely the, err, “gentleman’s appendage” functions in exactly the same way that an IUI would – by sort of shooting the sperm through the cervix, into the uterus?

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